iCaching is the all-in-one Geocache manager for the Mac.
It is a fast, native app with a real Mac userinterface like you’re used to from applications like iTunes. Available in the Mac App Store
There is a demo version available for download here:
If you get a ‘can’t be opened warning’, you can open the application by right click (or cmd-click), and choose the ‘Open’ menu item. In the following warning dialog click ‘Open’ and it will run normally from now on.